Potentially Universal Mechanism Of Aging Identified

Sirtuin genes have two functions: repair damaged DNA and regulate gene activity in cells. As DNA damage accumulated over time, however, the sirtuin became too distracted to properly regulate gene activity, and as a result, characteristics of aging set in.

“For ten years, this entire phenomenon in yeast was considered to be relevant only to yeast,” says Sinclair. “But we decided to test of this same process occurs in mammals.”

From Science Daily